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Prescribing in Pregnancy

All medicines cross the placenta to some extent.
 
When medicines are prescribed for pregnant women, either for acute or chronic conditions, weigh the potential benefits to the mother against the risk of adverse effects on the fetus/neonate.
 
Dosages of medicines may need to be adjusted during pregnancy as medicines may have altered pharmacokinetics, typically increased clearance due to increased organ blood flow and enzyme induction.

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General Advice

Effect of Medicines on Pregnancy, Fetus, or Neonate

Predictable Risks Based on Drug Activity

Effects of Pregnancy on Medicine Pharmacokinetics

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General Advice

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Effect of Medicines on Pregnancy, Fetus, or Neonate

Medicine toxicity in pregnancy, including teratogencity

Medicines with proven toxicity in humans

Note: occasionally a known teratogen may be clinically necessary, but alternatives should be considered. If used, this should be prescribed and supervised by a specialist – consult with Obstetric Medicine

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Predictable Risks Based on Drug Activity

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Effects of Pregnancy on Medicine Pharmacokinetics

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Topic Code: 93259