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Thiopurine Dosing Guideline in Immunosuppressive Therapy

1 in 200 individuals (0.5%) have severe TPMT deficiency which results in rapid life-threatening myelosuppression, usually within 7 to 10 days of initiating treatment.

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Definitions

Thiopurine Methyltransferase (TPMT)

Other Monitoring

6-TGN and 6-MMP Monitoring

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Definitions

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Thiopurine Methyltransferase (TPMT)

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Other Monitoring

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6-TGN and 6-MMP Monitoring

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Topic Code: 191833